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| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.contributor.advisor | Bastidas Caldés, Carlos Andrés | - |
| dc.creator | Monsalve Figueroa, Mishell Estefanía | - |
| dc.creator | Navarrete Játiva, María Daniela | - |
| dc.date.accessioned | 2019-04-01T16:47:21Z | - |
| dc.date.available | 2019-04-01T16:47:21Z | - |
| dc.date.issued | 2019 | - |
| dc.identifier.citation | Monsalve Figueroa, M. E.; Navarrete Játiva, M. D. (2019). Prevalencia de staphylococcus aureus resistente a meticilina y caracterización del factor de virulencia leucocidina panton-valentine asociado a factores de riesgos en estudiantes de la carrera de medicina de la Universidad de las Américas (Tesis de pregrado). Universidad de las Américas, Quito. | es_ES |
| dc.identifier.other | UDLA-EC-TIB-2019-01 | - |
| dc.identifier.uri | http://dspace.udla.edu.ec/handle/33000/10646 | - |
| dc.description | Staphylococcus aureus is a positive gram, facultative aerobic coccus and is related to important diseases in humans. This, has the ability to develop mechanisms of resistance to antibiotics and after the indiscriminate use of penicillin it was decided to develop a new type of this, known as methicillin. In 1961, the first strain of methicillin-resistant Staphylococcus aureus (MRSA) was reported. In addition, S. aureus has the capacity to produce toxins, including the Leucocidin Panton-Valentine (PVL) exotoxin, which gives the strain greater virulence and pathogenicity. Therefore, the objective of this study is to determine the prevalence of methicillin-resistant Staphylococcus aureus and to characterize the virulence factor Leucocidin Panton-Valentine associated with risk factors in students of the medical career at the University of the Americas. For this, a survey was conducted to the students to identify risk factors, later nasal and pharyngeal samples were collected from them. It was isolated and identified S. aureus. Following this, confirmed asylees were frozen as S. aureus. DNA extraction was performed and sensitivity to antibiotics was determined. The mecA and lukS-PV / lukF-PV gene were molecularly identified by a multiplex PCR. Finally, the statistical analysis of the results was carried out. We obtained 186 isolates of S. aureus, 109 of pharyngeal origin and 77 nasal. There were 149 isolates resistant to oxacillin in a phenotypic form, representing 46.27porcent. The prevalence of (PVL) is 1.86porcent and that of the mecA gene is 2.80porcent. The results of the resistance profile show that the isolates were resistant to 4 of 14 antibiotics, mainly penicillin and oxacillin. No resistance was shown to Vancomycin and Linezolid. The logistic regression analysis shows that the main factor associated with the presence of MRSA is having suffered a skin infection, having received antibiotics and taking a bath in a tub once a week. In conclusion, the prevalence of SASM, MRSA, mecA and PVL was determined, related to risk factors in a vulnerable population such as medical students. | en |
| dc.description.abstract | Staphylococcus aureus es un coco gram positivo, aerobio facultativo y está relacionado con enfermedades importantes en el ser humano... | es_ES |
| dc.format.extent | 115 p. | es_ES |
| dc.language.iso | spa | es_ES |
| dc.publisher | Quito: Universidad de las Américas, 2019 | es_ES |
| dc.rights | openAccess | es_ES |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/ec/ | es_ES |
| dc.subject | BACTERIOLOGÍA | es_ES |
| dc.subject | ENFERMEDADES INFECCIOSAS | es_ES |
| dc.subject | PIEL-ENFERMEDADES | es_ES |
| dc.title | Prevalencia de staphylococcus aureus resistente a meticilina y caracterización del factor de virulencia leucocidina panton-valentine asociado a factores de riesgos en estudiantes de la carrera de medicina de la Universidad de las Américas | es_ES |
| dc.type | bachelorThesis | es_ES |
| Aparece en las colecciones: | Ingeniería en Biotecnología | |
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