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dc.contributor.advisorBastidas Caldés, Carlos Andrés-
dc.creatorSalgado Garcés, María Soledad-
dc.date.accessioned2020-11-10T23:01:14Z-
dc.date.available2020-11-10T23:01:14Z-
dc.date.issued2020-
dc.identifier.citationSalgado, M. (2020). Revisión sistemática y metaanálisis del estado actual de la resistencia a la colistina en escherichia coli mediada por el gen mcr en cerdos, pollos y humanos en el mundo (Tesis de pregrado). Universidad de las Américas, Quito.es_ES
dc.identifier.otherUDLA-EC-TIB-2020-25-
dc.identifier.urihttp://dspace.udla.edu.ec/handle/33000/12699-
dc.descriptionSystematic reviews and meta-analyzes have proven to be a very useful tool to estimate the prevalence of bacteria resistant to different antimicrobials, because they are an important resource for decision-making in public health. Colistin is a last line antimicrobial for the treatment of infections caused by gram-negative microorganisms with multidrug-resistant. Antimicrobial resistance is a serious health problem worldwide, since bacteria such as Escherichia coli, which is considered the most common gram-negative microorganism, has evolved and developed different resistance mechanisms, making it difficult to treat infections. Colistin resistance in Escherichia coli can be mediated by chromosomal and plasmid mechanisms. The use of colistin in veterinary medicine in prophylactic treatment or as a growth promoter increases this problem. Accurate estimate of the overall prevalence caused by these mechanisms in their major hosts (chickens, pigs and humans) are necessary. Publications in the PubMed database published between December 31, 2015 to December 31, 2019 were identified and a total of 927 studies were obtained. 169 observational studies were included, and 160 studies were used for the meta-analysis. Colistinresistant bacterial isolates were reported in 54 countries on five continents and prevalence was reported in each one. Understanding the epidemiology of Escherichia coli with colistin-resistant in different regions of the world helps to expose information about how it is transmitted, and this can be used to reduce the risk of the appearance of zoonotic diseases and implement appropriate control programs.en
dc.description.abstractLas revisiones sistemáticas y metaanálisis han demostrado ser una herramienta muy útil para estimar la prevalencia de bacterias resistentes a diferentes antimicrobianos, porque constituyen una fuente importante para la toma de decisiones en la salud pública...es_ES
dc.format.extent136 p.es_ES
dc.language.isospaes_ES
dc.publisherQuito: Universidad de las Américas, 2020es_ES
dc.rightsopenAccesses_ES
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 Ecuador*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/ec/*
dc.subjectRESISTENCIA A LOS ANTIBIÓTICOSes_ES
dc.subjectBACTERIASes_ES
dc.subjectCOLISTINAes_ES
dc.titleRevisión sistemática y metaanálisis del estado actual de la resistencia a la colistina en escherichia coli mediada por el gen mcr en cerdos, pollos y humanos en el mundoes_ES
dc.typebachelorThesises_ES
Aparece en las colecciones: Ingeniería en Biotecnología

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