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http://dspace.udla.edu.ec/handle/33000/8690| Tipo de material : | bachelorThesis |
| Título : | Caracterización molecular de un brote nosocomial de Escherichia coli, productora de carbapenemasas, en un hospital público de Quito |
| Autor : | Ortiz Terreros, Lizeth Estefanía |
| Tutor : | Cordero Arroyo, Andrea Paola |
| Palabras clave : | INFECCIÓN NOSOCOMIAL;INFECCIONES BACTERIANAS;CARBAPENEMES;HOSPITALES;QUITO-ECUADOR |
| Fecha de publicación : | 2018 |
| Editorial : | Quito: Universidad de las Américas, 2018 |
| Citación : | Ortiz Terreros, L. E. (2018). Caracterización molecular de un brote nosocomial de Escherichia coli, productora de carbapenemasas, en un hospital público de Quito (Tesis de pregrado). Universidad de las Américas, Quito. |
| Resumen : | La palabra nosocomial es usada para definir a una enfermedad que fue adquirida por un paciente una vez que este ingresó al hospital, es un tipo de infección que se desarrolla en el periodo de 48 a 72 horas... |
| Descripción : | The word nosocomial is used to define a disease that was acquired by a patient once he was admitted to the hospital, it is a type of infection that develops in the period of 48 to 72 hours. The administration of an appropriate antibiotic therapy can be a mechanism of action against these infections. Some nosocomial infections are caused by Gram-negative enterobacteria, among which Escherichia coli stands out. The constant use of antibiotics in an excessive way has caused these enterobacteria to develop resistance to antibiotics, which has generated a great public health problem, since having this antibiotic resistance, treatment and control is more difficult, increasing the risk of morbidity and mortality of patients. It is for this reason that the present investigation aimed to analyze the clonality of Escherichia coli isolates causing nosocomial infections in the Hospital de Especialidades FFAA N 1, using a molecular system of epidemiological detection using DNA extraction, PCR, Electrophoresis and Sequencing It was possible to determine that the outbreak that existed in the hospital was of polyclonal origin, 3 important nodules were identified, of which ST 43, 2 and 24 stand out. The TS found in most of them are reported in Asian countries and others in Europe. It was possible to find new ST that are not reported in the database of the Pasteur Institute (France), it was also possible to show that the outbreak was variant in time, that is to say that throughout the study it presented months with high rates of infections and others very low. |
| URI : | http://dspace.udla.edu.ec/handle/33000/8690 |
| Aparece en las colecciones: | Ingeniería en Biotecnología |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| UDLA-EC-TIB-2018-01.pdf | 1,94 MB | Adobe PDF | Visualizar/Abrir |
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