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http://dspace.udla.edu.ec/handle/33000/11447Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.contributor.advisor | Armijos Jaramillo, Vinicio Danilo | - |
| dc.creator | Espinosa Viteri, Nicole Andrea | - |
| dc.creator | Vizcaíno Cárdenas, Karla Stephanie | - |
| dc.date.accessioned | 2019-09-18T16:18:30Z | - |
| dc.date.available | 2019-09-18T16:18:30Z | - |
| dc.date.issued | 2019 | - |
| dc.identifier.citation | Espinosa Viteri, N. A.; Vizcaíno Cárdenas, K. S. (2019). Detección de eventos de mimetismo molecular en el proteoma del patógeno de maíz Ustilago maydis (Tesis de pregrado). Universidad de las Américas, Quito. | es_ES |
| dc.identifier.other | UDLA-EC-TIB-2019-26 | - |
| dc.identifier.uri | http://dspace.udla.edu.ec/handle/33000/11447 | - |
| dc.description | Molecular mimicry is one of the evolutionary strategies that pathogens use to manipulate host metabolism and functions. Several strategies have been designed to detect cases of molecular mimicry in silica; However, a model has not been developed to detect this phenomenon in plant-pathogenic systems. As such, this work developed for the first time an in silico method to detect mimetic candidates, using the Ustilago maydis-Zea mays patosystem as a model. In this methodology, a sequence comparison between the proteome of the pathogen, the host and non-phytopathogenic fungi was used. In addition, the subcellular location of the mimicked-imitated candidates was determined. On the other hand, RNA-seq information was used to identify the co-expression of the candidates. Among the most important candidates obtained by this method are: UDP-glucose: glycoprotein glycosyltransferase, Diaphanous-related Formin, Phospholipid: diacylglycerol acyltransferase 1. These three proteins are involved in cell division, and plant establishment of the response to pathogens . For this reason, these are candidates with potential to manipulate plant cells for the benefit of the pathogen. | en |
| dc.description.abstract | El mimetismo molecular es una de las estrategias evolutivas que utilizan los patógenos para manipular el metabolismo y las funciones del huésped. Se han diseñado varias estrategias para detectar casos de mimetismo molecular in sílico… | es_ES |
| dc.format.extent | 53 p. | es_ES |
| dc.language.iso | spa | es_ES |
| dc.publisher | Quito: Universidad de las Américas, 2019 | es_ES |
| dc.rights | openAccess | es_ES |
| dc.rights | Atribución-NoComercial-SinDerivadas 3.0 Ecuador | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/ec/ | * |
| dc.subject | BIOTECNOLOGÍA | es_ES |
| dc.subject | BIOLOGÍA MOLECULAR | es_ES |
| dc.subject | MIMETISMO MOLECULAR | es_ES |
| dc.title | Detección de eventos de mimetismo molecular en el proteoma del patógeno de maíz Ustilago maydis | es_ES |
| dc.type | bachelorThesis | es_ES |
| Aparece en las colecciones: | Ingeniería en Biotecnología | |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| UDLA-EC-TIB-2019-26.pdf | 719,89 kB | Adobe PDF | Visualizar/Abrir |
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