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Tipo de material : bachelorThesis
Título : Análisis comparativo de los perfiles hematológicos entre indígenas kichwas que residen sobre los 2500 msnm versus sus pares amazónicos que residen bajo los 200 msnm
Autor : Portilla Cisneros, David Sebastián
Tutor : Ortiz Prado, Esteban
Palabras clave : HEMATOLOGÍA;ENFERMEDADES-PREVENCIÓN;PACIENTES;ENFERMEDAD CARDIOVASCULAR;REGIÓN SIERRA;REGIÓN AMAZÓNICA
Fecha de publicación : 2018
Editorial : Quito: Universidad de las Américas, 2018
Citación : Portilla Cisneros, D. S. (2018). Análisis comparativo de los perfiles hematológicos entre indígenas kichwas que residen sobre los 2500 msnm versus sus pares amazónicos que residen bajo los 200 msnm (Tesis de pregrado). Universidad de las Américas, Quito.
Resumen : Antecedentes: La exposición a la altura e hipoxia hipobárica a largo plazo, ocasiona respuestas adaptativas a nivel hematológico en los seres humanos...
Descripción : Background: Long-term exposure to hypobaric hypoxia and hypoxia causes adaptive responses at hematological level in humans. The difference in hemoglobin concentrations or analysis of the lipid profile have been previously reported; However, in populations with similar genetic characteristics that come from the same ethnological root and that reside in a different geographical area, they have not been analyzed in Ecuador. The objective of this study is to determine if there are differences in the hematological parameters, lipid profile and cardiovascular risk in Kichwa de la Sierra and Kichwa people of the Amazon. Methodology: An analytical observational cross-sectional study was conducted in the Kichwa population of Oyacachi (3180 masl) and the Kichwa population of Limoncocha (230 masl), collecting a general physical examination and evaluation of the hematological profile, glucose levels and lipid profile. For the analysis, descriptive and inferential statistics were made, the hypothesis test being used to use an independent T-Test of equal or unequal variances according to the results of the Levine test. Results: The number of patients in Oyacachi was 95 (41 percent men and 59 percent women) and Limoncocha 118 (33 percent men and 67 percent women). Significant differences were found in the erythrocytes men (p equal 0.003 IC: -1.076-0.235) women (p equal 0.0001 IC: -0.8 - -0.65). Hemoglobin (p equal 0.032 IC: -2.2 - 0.106). Hematocrit (p equal 0.0001 IC: -10.1--5.28). The lipid profile showed differences in Cholesterol (p equal 0.0001 CI: -32.4-14.0). Triglycerides (p equal 0.002 CI: 11.3-52.2). LDL (p equal 0.0001 IC: -13.4 - -6.3). HDL (p equal 0.0001 IC: -26.5 --11.0). Finally, no significant differences were demonstrated in White Globules (p equal 0.11 IC: 0.195 -1.5). Platelets women (p equal 0.125 CI: -30.27. -3.75), men (p equal 0.582 CI: -33.23- 18.79), Glucose (p equal 0.435 IC: -7.84- 3.39) and Cardiovascular Risk (p equal 0.273) IC: -0.16-0.56). Conclusions: Living at altitude for prolonged periods of time has known adaptive effects: the number of erythrocytes, the amount of hemoglobin, hematocrit and serum glucose. There are differences in the lipid profile, with higher levels of cholesterol and high density and low density lipoproteins in height versus their Amazonian peers; however, the calculated cardiovascular risk did not show significant differences.
URI : http://dspace.udla.edu.ec/handle/33000/10342
Aparece en las colecciones: Medicina

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